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Severe toxicity Toxicity Dosage Calculation manifests as fulminant liver failure Liver failure Severe inability of the liver to perform its normal metabolic functions, as evidenced by severe jaundice and abnormal serum levels of ammonia

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Hierarchical clustering analyses showed an association between brain IR and specific clinical symptoms, with the highest levels of IRS-1 in L1CAM exosomes associated with suicidality, anhedonia, depressed mood and feelings of guilt

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